Atmospheric oxygen mediated synthesis of pyrazole under visible irradiation

作者:Yadav Snehlata; Rai Pratibha; Srivastava Madhulika; Singh Jaya; Tiwari Kamla Prasad; Singh Jagdamba
来源:Tetrahedron Letters, 2015, 56(43): 5831-5835.
DOI:10.1016/j.tetlet.2015.07.039

摘要

A novel protocol has been reported for synthesis of pyrazoles by visible light irradiation in the presence of eosin Y, an organophotocatalyst under atmospheric oxygen. We have successfully carried out a visible light induced Michael addition followed by intramolecular cyclization reactions for the formation of heterocyclic ring. The present method incorporates advantages such as being eco-friendly, involving metal free condition, reporting excellent yields, using minimum reaction time, making use of an easily available catalyst, and eliminating the use of column chromatography.

  • 出版日期2015-10-21