Dynamic microwave-assisted extraction of flavonoids from Radix scutellariae

作者:You Jing yan; Zhang Hua rong; Ding Lan; Xiao Ting ting; Zhang Han qi; Song Da qian*
来源:Chemical Research in Chinese Universities, 2007, 23(2): 148-153.
DOI:10.1016/S1005-9040(07)60031-2

摘要

Dynamic microwave-assisted extraction (DMAE) of flavonoids from Radix Scutellarie was described in this article. A TM010 microwave resonant cavity was used as the energy coupler. Several parameters of DMAE, including concentration, flow rate, volume of the extraction solvent, and irradiation power, were optimized. The extraction was performed under the optimum conditions for the extraction of total flavonoids. The total flavonoids were determined by UV-Vis spectrophotometry. The main bioactive components, including baicalin, baicalein, and wogonin, were determined by HPLC. The extraction yields of the flavonoids obtained by DMAE were compared with those obtained by pressurized microwave assisted extraction (PMAE), ultrasonic extraction (UE), soxhlet extraction (SE), and reflux extraction (RE), and these results indicate that DMAE is a good alternative method for the extraction of flavonoids from Radix Scutellarie.