Development of polysaccharide-based membranes incorporating the bioactive compound aloin

作者:Krause Bierhalz Andrea Cristiane; Lopes Selma Aparecida; Resende Pires Ana Luiza; Moraes Angela Maria
来源:International Journal of Polymeric Materials and Polymeric Biomaterials, 2017, 66(4): 193-202.
DOI:10.1080/00914037.2016.1201762

摘要

Chitosan-alginate (CA) and chitosan-xanthan (CX) membranes containing aloin were developed for use as wound dressings. The effects of aloin-to-biopolymer ratio on membranes morphology, aspect, liquid uptake, mass loss, mechanical properties, thermal behavior, aloin incorporation efficiency, and release kinetics were analyzed. CA membranes showed higher stability in liquid media and greater elongation at break. CX membranes had more homogeneous microstructure and slightly higher tensile strength. The opacity and color intensity of both formulations increased with aloin incorporation. Maximum aloin incorporation efficiencies were 56.0% and 79.5% in CA and CX membranes, respectively, and slower aloin release was observed for CA membranes. [GRAPHICS] .

  • 出版日期2017