摘要

Bronchial hyperreactivity is a characteristic feature of asthma. There are a number of methods used for bronchial provocation and the agents used can be classed as direct and indirect. Methacholine, a direct stimulant, is probably the most sensitive agent used in the diagnosis of asthma with, however, reservations about this measure because of its low specificity. In contrast, mannitol, an indirect stimulant, has better specificity and appears to be a promising agent that might be used in the follow-up of asthmatic patients, but its role remains to be confirmed.

  • 出版日期2013-4

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