MicroRNAs - keeping cells in formation

作者:Miska Eric A*
来源:Nature Cell Biology, 2008, 10(5): 501-502.
DOI:10.1038/ncb0508-501

摘要

During epithelial - mesenchymal transition (EMT) cells loosen their intercellular contacts and leave the epithelial layer. Three microRNA ( miRNA) families modulate EMT upstream of the key cell-adhesion protein E- cadherin, highlighting the potential importance of miRNAs in EMT- dependent processes, such as mesoderm development and tumour metastasis.

  • 出版日期2008-5

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