A 12-lead ECG-method for quantifying ischemia-induced QRS prolongation to estimate the severity of the acute myocardial event

作者：Elmberg Viktor; Almer Jakob; Pahlm Olle; Wagner Galen S; Engblom Henrik; Ringborn Michael^*

来源：Journal of Electrocardiology, 2016, 49(3): 272-277.

DOI：10.1016/j.jelectrocard.2016.02.001

• Electrocardiography
• Ischemia
• ECG
• Acute myocardial infarction
• Severity of ischemia

Introduction: Studies have shown terminal QRS distortion and resultant QRS prolongation during ischemia to be a sign of low cardiac protection and thus a faster rate of myocardial cell death. A recent study introduced a single lead method to quantify the severity of ischemia by estimating QRS prolongation. This paper introduces a 12-lead method that, in contrast to the previous method, does not require access to a prior ECG.
Methods: QRS duration was estimated in the lead that showed the maximal ST deviation according to a novel method. The degree of prolongation was determined by subtracting the measured QRS duration in the lead that showed the least ST deviation.
Results: The method is demonstrated in examples of acute occlusion in two of the major coronary arteries.
Conclusion: This paper presents a 12-lead method to quantify the severity of ischemia, by measuring QRS prolongation, without requiring comparison with a previous ECG.

• 出版日期2016-6