A REVIEW OF THE PHARMACOLOGICAL MECHANISM OF TRADITIONAL CHINESE MEDICINE IN THE INTERVENTION OF CORONARY HEART DISEASE AND STROKE

作者：Zhang, Wenting^*; Gao, Kuo; Liu, Jingwei; Zhao, Huihui; Wang, Juan; Li, Yubo; Murtaza, Ghulam; Chen, Jianxin; Wang, Wei

来源：African Journal of Traditional, Complementary and Alternative Medicines, 2013, 10(6): 532-537.

DOI：10.4314/ajtcam.v10i6.24

• Buyang Huanwu Decoction (BHD)
• Brain-Heart concurrent treatment
• Pharmaceutical effect mechanism
• Material basis

In recent years, several researches have showed that Buyang Huanwu Decoction (BHD) possesses multiple target points in the intervention of diseases, and has same treatment effects on cerebrovascular diseases and cardiovascular diseases. But, there was no full report about the mechanistic and material basis in Brain-Heart concurrent treatment. The objective of the present study was to examine the pharmacological mechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. We combined the HIT, PubChem, David Database resource and the networked pharmacology method to ultimately find out BHD's thirty-five potential brain-heart concurrent treatment target points, and preliminarily reveal BHD's material basis for treatment of cerebrovascular diseases and cardiovascular diseases. Finally, the study provided new information with the guidance meanings.

• 出版日期2013
• 单位北京中医药大学