Wave Intensity Analysis Can Identify Eccentric Cardiac Hypertrophy in Hypertensive Patients With Varied Left Ventricular Configurations

作者：Du, Guo-Qing; Li, Hai-Ru; Xue, Jing-Yi; Chen, Shuang; Du, Pei; Wu, Yan; Tian, Jia-Wei^*

来源：Journal of Ultrasound in Medicine, 2015, 34(11): 2019-2027.

DOI：10.7863/ultra.14.12007

• blood pressure
• echocardiography
• hypertension
• left ventricular configuration
• wave intensity

Objectives-The primary aim of this study was to determine whether wave intensity can discriminate cases of eccentric hypertrophy in patients with essential hypertension who have varied left ventricular configurations.
Methods-A total of 155 hypertensive patients with different ventricular configurations (27 normal configuration, 42 concentric remodeling 62 concentric hypertrophy, and 24 eccentric hypertrophy) were recruited. We performed a noninvasive wave intensity analysis of the common carotid artery and conventional echocardiography. Blood pressure and flow velocity were measured in the right carotid artery of all patients.
Results-The left ventricular ejection fraction (LVEF) in the eccentric hypertrophy group was significantly lower than the values in the other groups (P < .05). The R-W-1 interval/W-1-W-2 interval ratio (where W-1 indicates the first positive peak and W-2 the second positive peak) in the eccentric hypertrophy group was much higher than the values in the other groups (P < .05). However, there were no significant differences in W-1, W-2, and negative area among these groups. Pearson correlation analysis showed that R-W-1/W-1-W-2, R-W-1, and W-1-W-2 were correlated with the LVEF, whereas there was no correlation between W-1, W-2, negative area, and the reflection coefficient with the LVEF.
Conclusions-We propose that by using the R-W-1/W-1-W-2 ratio, wave intensity analysis can identify hypertensive patients with eccentric hypertrophy without the need for echocardiography.

• 出版日期2015-11
• 单位哈尔滨医科大学