Minimal Change Nephrotic Syndrome Which Was Most Likely Caused by Chronic Sinusitis

作者：Iwatani Hirotsugu; Mori Daisuke; Yamamoto Satoko; Nakano Chikako; Yamamoto Ryohei; Masumura Chisako; Shikina Takashi; Imai Takao; Inohara Hidenori; Rakugi Hiromi; Isaka Yoshitaka^*

来源：Internal Medicine, 2015, 54(18): 2373-2375.

DOI：10.2169/internalmedicine.54.4480

• chronic sinusitis
• minimal change nephrotic syndrome (MCNS)

A 33-year-old Japanese man was admitted with severe edema, and a renal biopsy confirmed minimal change nephrotic syndrome (MCNS). CT revealed his severe chronic sinusitis, and he first received antimicrobial therapy, which resulted in decreased proteinuria. The surgical operation for sinusitis resulted in the complete disappearance of proteinuria without corticosteroid or immunosuppressant therapy within one week. MCNS may be triggered by infection, but there are no previously reported cases of MCNS that is completely remitted by infection control alone. Therefore, we herein report the first case of MCNS that attained complete remission following therapy for chronic sinusitis alone, which suggests a strong etiology of chronic sinusitis for MCNS.

• 出版日期2015