Magnet-PNIPA hydrogels for bioengineering applications

作者：Ramanujan R V^*; Ang K L; Venkatraman S

来源：Journal of Materials Science, 2009, 44(5): 1381-1387.

DOI：10.1007/s10853-006-1064-x

Temperature-sensitive Poly (N-isopropylacrylamide), PNIPA gels were synthesized with micron-sized iron and iron oxide (Fe(3)O(4)) particles to investigate their viability for hyperthermia applications. Induction heating of the magnetic hydrogels with varying concentration of magnetic powder was conducted at a frequency of 375 kHz for magnetic field strength varying from 1.7 kA/m (21 Oe) to 2.5 kA/m (31.4 Oe). It was observed that the maximum temperature induced in the magnetic hydrogels increased with the concentration of magnetic particles and magnetic field strength. The PNIPA gel underwent a collapse transition at 34 A degrees C. It was found that a 2.5 wt.% Fe(3)O(4) in PNIPA composite took 260 s to be heated to 45 A degrees C under a magnetic field strength of 1.7 kA/m, the specific absorption rate (SAR) was found to be 1.83. SAR of iron oxide was found to be higher than the SAR of iron.

• 出版日期2009-3
• 单位南阳理工学院