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Akt inhibitor enhances apoptotic effect of carboplatin on human epithelial ovarian carcinoma cell lines
Akt Cys-310-targeted Inhibition by Hydroxylated Benzene Derivatives Is Tightly Linked to Their Immunosuppressive Effects
Akt activity protects rheumatoid synovial fibroblasts from Fas-induced apoptosis by inhibition of Bid cleavage
Akt regulates the expression of MafK, synaptotagmin I, and syntenin-1, which play roles in neuronal function
Akt and phosphoinositide regulation and wortmannin-dependent induction of phospho-Akt in 3T3-L1 adipocytes on cold exposure followed by rewarming
Akt expression in mouse oocytes matured in vivo and in vitro
Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts
Akt A double-edged sword for hematopoietic stem cells
Akt is activated in chronic lymphocytic leukemia cells and delivers a pro-survival signal: the therapeutic potential of Akt inhibition
Akt signaling in platelets and thrombosis
Akt is required for Stat5 activation and mammary differentiation
Akt Deficiency Attenuates Muscle Size and Function but Not the Response to ActRIIB Inhibition
Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease
Akt Phosphorylation at Ser473 Predicts Benefit of Paclitaxel Chemotherapy in Node-Positive Breast Cancer
Akt Downregulation by Flavin Oxidase-Induced ROS Generation Mediates Dose-Dependent Endothelial Cell Damage Elicited by Natural Antioxidants
Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells
Akt Specific Activator SC79 Protects against Early Brain Injury following Subarachnoid Hemorrhage
Akt phosphorylates myc-associated zinc finger protein (MAZ), releases P-MAZ from the p53 promoter, and activates p53 transcription
Akt Activation Correlates with Snail Expression and Potentially Determines the Recurrence of Prostate Cancer in Patients at Stage T2 after a Radical Prostatectomy
Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS
Akt activation correlates with the tumor aggressiveness in Tunisian patients with bladder cancer
Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition
Akt regulates progesterone receptor B-dependent transcription and angiogenesis in endometrial cancer cells
Akt and beta-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line
Akt isoform-dependent regulation of ATP-Binding cassette A1 expression by apolipoprotein E
Akt and PI3K-dependent but CREB-independent upregulation of MCAM by endothelin-3 in human melanocytes
Akt signal transduction dysfunction in Parkinson's disease
Akt as a therapeutic target in cancer
Akt signaling pathway: a target for radiosensitizing human malignant glioma
Akt isoforms and glucose homeostasis - the leptin connection
Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells
Akt induces down regulation of MUC5AC production in NCI-H292 human airway epithelial cells cultured on extracellular matrix
Akt Phosphorylates Both Tsc1 and Tsc2 in Drosophila, but Neither Phosphorylation Is Required for Normal Animal Growth
Akt Regulates IL-10 Mediated Suppression of TNF alpha-Induced Cardiomyocyte Apoptosis by Upregulating Stat3 Phosphorylation
Akt phosphorylation is required for heat acclimation-induced neuroprotection
Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination
Akt protects the heart against ischaemia-reperfusion injury by modulating mitochondrial morphology
Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cells
Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury
Akt Phosphorylation and Regulation of Transketolase Is a Nodal Point for Amino Acid Control of Purine Synthesis
Akt and p53 are potential mediators of reduced mammary tumor growth by Chloroquine and the mTOR inhibitor RAD001
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
Akt pathway as a target for therapeutic intervention in HNSCC
Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila
Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition
Akt Inhibitor Akt-IV Blocks Virus Replication through an Akt-Independent Mechanism
Akt Increases Sox2 Expression in Adult Hippocampal Neural Progenitor Cells, but Increased Sox2 Does Not Promote Proliferation
Akt isoform-specific signaling in breast cancer Uncovering an anti-migratory role of palladin
Akt Phosphorylation of Merlin Enhances Its Binding to Phosphatidylinositols and Inhibits the Tumor-Suppressive Activities of Merlin
Akt Signaling Is Associated with the Berberine-Induced Apoptosis of Human Gastric Cancer Cells
Akt kinases in breast cancer and the results of adjuvant therapy
Akt activity in endometrial cancer cells: Regulation of cell survival through cIAP-1
Akt as a Victim, Villain and Potential Hero in Parkinson's Disease Pathophysiology and Treatment
Akt activates NOS3 and separately restores barrier integrity in H(2)O(2)-stressed human cardiac microvascular endothelium
Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscle
Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis
Akt signalling in health and disease
Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function
Akt Inhibition Promotes ABCA1-Mediated Cholesterol Efflux to ApoA-I through Suppressing mTORC1
Akt signalling parameters are different in oncocytomas compared to renal cell carcinoma
Akt recruits Dab2 to albumin endocytosis in the proximal tubule
Akt regulates beta-catenin in a rat model of focal cerebral ischemia-reperfusion injury
Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes
Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab
Akt Signaling Leads to Stem Cell Activation and Promotes Tumor Development in Epidermis
Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis
Akt and ERK Control the Proliferative Response of Mammary Epithelial Cells to the Growth Factors IGF-1 and EGF Through the Cell Cycle Inhibitor p57(Kip2)
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells
Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells
Akt Activation Emulates Chk1 Inhibition and Bcl2 Overexpression and Abrogates G2 Cell Cycle Checkpoint by Inhibiting BRCA1 Foci
Akt phosphorylation of zyxin mediates its interaction with acinus-S and prevents acinus-triggered chromatin condensation
Akt phosphorylates Mstl and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation
Akt kinase: a key regulator of metabolism and progression of tumors
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer
Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin-induced cell death
Akt is altered in an animal model of Huntington's disease and in patients
Akt substrate TBCM regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes
Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts
Akt inhibitors in clinical development for the treatment of cancer
Akt is a direct target for myricetin to inhibit cell transformation
Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue
Akt and PTEN: beta-cell mass and pancreas plasticity