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Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis
Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor
Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells
Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation
Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors
Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1
Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death
Akt phosphorylates and regulates Pdcd4 tumor suppressor protein
Akt in prostate cancer: Possible role in androgen-independence
Akt regulates L-type Ca2+ channel activity by modulating Ca-v alpha 1 protein stability
Akt Inhibitors MK-2206 and Nelfinavir Overcome mTOR Inhibitor Resistance in Diffuse Large B-cell Lymphoma
Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity
Akt and c-Myc Induce Stem-Cell Markers in Mature Primary p53(-/-) Astrocytes and Render These Cells Gliomagenic in the Brain of Immunocompetent Mice
Akt phosphorylation in human chondrocytes is regulated by p53R2 in response to mechanical stress
Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase
Akt or phosphoinositide-3-kinase inhibition reverses cardio-protection in Toll-like receptor 2 deficient mice
Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells
Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells
Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation
Akt down-modulation induces apoptosis of human prostate cancer cells and synergizes with EGFR tyrosine kinase inhibitors
Akt promotes BMP2-mediated osteoblast differentiation and bone development
Akt Activation Synergizes with Trp53 Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma
Akt Promotes Post-Irradiation Survival of Human Tumor Cells through Initiation, Progression, and Termination of DNA-PKcs-Dependent DNA Double-Strand Break Repair
Akt Interaction with PLC gamma Regulates the G(2)/M Transition Triggered by FGF Receptors from MDA-MB-231 Breast Cancer Cells
Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli
Akt isoforms differentially regulate neutrophil functions
Akt pathway in oncogenesis and as a target for anti-cancer therapy
Akt cross-links IL-4 priming, stem cell factor signaling, and IgE-dependent activation in mature human mast cells
Akt inactivation induces endoplasmic reticulum stress-independent autophagy in fibroblasts from patients with Pompe disease
Akt is an essential player in regulating cell/organ growth at the adult stage in the hard tick Haemaphysalis longicornis
Akt is upstream and MAPKs are downstream of NF-kappa B in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism
Akt signaling is required for glioblastoma maintenance in vivo
Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors
Akt signaling and growth of the heart
Akt Activation is Required for TGF-beta 1-Induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts
Akt Phosphorylates Sec24: New Clues into the Regulation of ER-to-Golgi Trafficking
Akt acutely activates the cholesterogenic transcription factor SREBP-2
Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization
Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398
Akt signaling is critical for memory CD8(+) T-cell development and tumor immune surveillance
Akt signaling as a mediator of cardiac adaptation to low birth weight
Akt enhances nerve growth factor-induced axon growth via activating the Nrf2/ARE pathway
Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway
Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1
Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop
Akt isoform specific effects in ovarian cancer progression
Akt activation by Evodiae Fructus extract protects ovary against 4-vinylcyclohexene diepoxide-induced ovotoxicity
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways (vol 14, pg 21, 2011)
Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle
Akt and mTOR in B cell activation and differentiation
Akt Contributes to Activation of the TRIF-Dependent Signaling Pathways of TLRs by Interacting with TANK-Binding Kinase 1
Akt Fine-tunes NF-kappa B-dependent Gene Expression during T Cell Activation
Akt inhibition improves long-term tumour control following radiotherapy by altering the microenvironment
Akt activation by Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) in ovarian cancer cells
Akt phosphorylates and regulates the function of Dlx5
Akt phosphorylates and regulates the osteogenic activity of Osterix
Akt isoform-specific inhibition of MDA-MB-231 cell proliferation
Akt as a target for cancer therapy: more is not always better (lessons from studies in mice)
Akt signaling dynamics in individual cells
Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study
Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels
Akt Serine/Threonine Kinase 1 Regulates de Novo Fatty Acid Synthesis through the Mammalian Target of Rapamycin/Sterol Regulatory Element Binding Protein 1 Axis in Dairy Goat Mammary Epithelial Cells
Akt drives buffalo casein-derived novel peptide-mediated osteoblast differentiation
Akt activation improves microregional oxygen supply/consumption balance after cerebral ischemia-reperfusion
Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3
Akt modulation by miR-145 during exercise-induced VSMC phenotypic switching in hypertension
Akt regulates neurite growth by phosphorylation-dependent inhibition of radixin proteasomal degradation
Akt Inhibitor Perifosine Prevents Epileptogenesis in a Rat Model of Temporal Lobe Epilepsy
Akt activation: A potential strategy to ameliorate insulin resistance
Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells
Akt, AS160, metabolic risk factors and aerobic fitness in middle-aged women
Akt, FoxO and regulation of apoptosis
Akt, 14-3-3 zeta zeta, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma
Akt, mTOR and NF-kappa B pathway activation in Treponema pallidum stimulates M1 macrophages
Akt-FOXO3a signaling axis dysregulation in human oral squamous cell carcinoma and potent efficacy of FOXO3a-targeted gene therapy
Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells
Akt-mTOR signaling is involved in Notch-1-mediated glioma cell survival and proliferation
Akt- and foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis
Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration
Akt-mediated transforming growth factor-beta 1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cells
Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity
Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?
Akt- ivation of RNA Splicing