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The complete exon-intron structure of the 156-kb human gene NFKB1, which encodes the p105 and p50 proteins of transcription factors NF-kappa B and I kappa B-gamma: Implications for NF-kappa B-mediated signal transduction
The organization of the gene (EPB72) encoding the human erythrocyte band 7 integral membrane protein (protein 7.2b)
The road to HIV-1 integrase inhibitors: the case for supporting basic research
The Origin of Lentivirus Research: Maedi-Visna Virus
The early history of tumor virology: Rous, RIF, and RAV
The Development of Combination Therapies for HIV Infection
The reverse transcriptase of HIV-1: role of the domain connection and RNase H in anti-retroviral resistors
The Coordinates of Truth
The Principle of Recursive Genome Function
The discovery of the first human retrovirus: HTLV-1 and HTLV-2
The use of reverse transcriptase for efficient first- and second-strand cDNA synthesis from single- and double-stranded RNA templates
The discovery of endogenous retroviruses
The eureka enzyme: the discovery of DNA polymerase
The general transcription machinery and general cofactors
The first strand transfer reaction of HIV-1 reverse transcription is more efficient in infected cells than in cell-free natural endogenous reverse transcription reactions
The road to Src
The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain
The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3 '[3H]indol]-2 '(1 ' H)-ones as Orally Bioavailable Antitumor Agents
The structure of ibuprofen bound to cyclooxygenase-2
The Megavirus Chilensis Cu,Zn-Superoxide Dismutase: the First Viral Structure of a Typical Cellular Copper Chaperone-Independent Hyperstable Dimeric Enzyme
The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding
The Outcome of Patients Treated with Sunitinib Prior to Planned Nephrectomy in Metastatic Clear Cell Renal Cancer
The Role of Surgery in Advanced Renal Cell Carcinoma: Cytoreductive Nephrectomy and Metastasectomy
The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer
The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas
The Role of mTOR Inhibition in Renal Transplant Immune Suppression
The Mammalian Target of Rapamycin Pathway Is Widely Activated Without PTEN Deletion in Renal Cell Carcinoma Metastases
The Impact of Cytoreductive Nephrectomy on Survival of Patients With Metastatic Renal Cell Carcinoma Receiving Vascular Endothelial Growth Factor Targeted Therapy
The Scramble conversion tool
The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
The mechanism of membrane-associated steps in tail-anchored protein insertion
The Crystal Structure of the Human Co-Chaperone P58(IPK)
The crystal structure of a voltage-gated sodium channel
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites
The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains
The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails
The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by beta Strand Switching
The Virulence Factor PEB4 (Cj0596) and the Periplasmic Protein Cj1289 Are Two Structurally Related SurA-like Chaperones in the Human Pathogen Campylobacter jejuni
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
The role of active-site Phe87 in modulating the organic co-solvent tolerance of cytochrome P450 BM3 monooxygenase
The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates
The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism
The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft
The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity
The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein
The structure of an orthorhombic crystal form of a %26apos;forced reduced%26apos; thiol peroxidase reveals lattice formation aided by the presence of the affinity tag
The precursor form of Hansenula polymorpha copper amine oxidase 1 in complex with Cu-I and Co-II
The structure of Ca2+-loaded S100A2 at 1.3-angstrom resolution
The advantages of co-culture over mono cell culture in simulating in vivo environment
The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through beta 1 integrin
The UCSC Interaction Browser: multidimensional data views in pathway context
The burden of faulty proofreading in colon cancer
The dynamics of LTR retrotransposon accumulation across 25 million years of panicoid grass evolution
The Unusual Case of Porcupine
The impact of transposable elements on eukaryotic genomes: From genome size increase to genetic adaptation to stressful environments
The TNP1 haplotype - GCG is associated with azoospermia
The effect of SNP discovery method and sample size on estimation of population genetic data for Chinese and Indian rhesus macaques (Macaca mulatta)
The Missing Association: Sequencing-Based Discovery of Novel SNPs in VKORC1 and CYP2C9 That Affect Warfarin Dose in African Americans
The rise and fall of cancer mortality in the USA: why does pancreatic cancer not follow the trend?
The VeinViewer Vascular Imaging System Worsens First-Attempt Cannulation Rate for Experienced Nurses in Infants and Children with Anticipated Difficult Intravenous Access
The role of ambient ice-like water adlayers formed at the interfaces of graphene on hydrophobic and hydrophilic substrates probed using scanning probe microscopy
The burden of bladder cancer in men and women: analysis of the years of life lost
The adenoma hunt in colorectal cancer screening: defining the target
The FGFR3 Mutation is Related to Favorable pT1 Bladder Cancer
The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers
The role of patient-provider communication for black women making decisions about breast cancer treatment
The dilemma of cystectomy in old-old and oldest-old patients
The uncertain relationship between obesity and prostate cancer: An Italian biopsy cohort analysis
The predictive value of mean platelet volume in differential diagnosis of non-functional pancreatic neuroendocrine tumors from pancreatic adenocarcinomas
The role of lymphovascular space invasion in renal cell carcinoma as a prognostic marker of survival after curative resection
The omega-rho meson mass splitting and mixing from lattice QCD
The charm quark mass from non-relativistic sum rules
The slow cell death response when screening chemotherapeutic agents
The subtypes of peroxisome proliferator-activated receptors expressed by human podocytes and their role in decreasing podocyte injury
The effect of atomic hydrogen adsorption on single-walled carbon nanotubes properties
The adsorption properties of surface modified activated carbon fibers for hydrogen storages
The carbon-silicon bond cleavage of organosilicon compounds in supercritical water
The oxidation of alcohols in N-oxyl-immobilized silica gel/aqueous NaOCl disperse systems. A prominent access to a column-flow system
The effect of pH control on the selective ruthenium-catalyzed oxidation of ethers and alcohols with sodium hypochlorite
The effects of material properties on the activity of sol-gel entrapped perruthenate under supercritical conditions
The use of hydrophilic groups in aqueous organic reactions