Differential pulse adsorption voltammetry for determination of procaine hydrochloride at a pumice modified carbon paste electrode in pharmaceutical preparations and urine

作者：Wang CY; Hu XY^*; Jin GD; Leng ZZ

来源：Journal of Pharmaceutical and Biomedical Analysis, 2002, 30(1): 131-139.

DOI：10.1016/S0731-7085(02)00204-2

• procaine hydrochloride
• pumice
• carbon paste electrode
• differential pulse voltammetry
• urine

Procaine hydrochloride was determined by the differential pulse voltammetry (DPV) using a 6% (m/m) pumice modified carbon paste electrode in 1.25 x 10(-3) mol l(-1) KH2PO4 and Na2HPO4 buffer solution (pH 6.88, 25 degreesC). The anodic peak potential used was + 0.980 V (vs. SCE). A good linear relationship was realized between the anodic peak current and procaine concentration in the range of 9.0 x 10(-7)-2.6 x 10(-5) mol l(-1) with the detection limit of 5.0 x 10(-8) mol l(-1). The recovery was 95.2-104.8% with the relative standard deviation of 3.2% (n = 10). The pharmaceutical preparations, procaine hydrochloride injection and the urine samples were determined with the desirable results.

• 出版日期2002-8-22
• 单位扬州大学