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Substrate specificity of Staphylococcus hyicus lipase and Staphylococcus aureus lipase as studied by in vivo chimeragenesis
Substitutions of the highly conserved M2 leucine create spontaneously opening rho 1 gamma-aminobutyric acid receptors
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor
Substitution of Met-69 by Ala or Gly in TEM-1 beta-lactamase confer an increased susceptibility to clavulanic acid and other inhibitors
Substance Use and HIV Risk Behavior among Men Who Have Sex with Men: The Role of Sexual Compulsivity
Substrate-mediated interactions of Pt atoms adsorbed on single-wall carbon nanotubes: Density functional calculations
Substrate depletion approach for determining in vitro metabolic clearance: Time dependencies in hepatocyte and microsomal incubations
Substrate-induced DNA Polymerase beta Activation
Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting
Substrate determinants for RNA editing and editing complex interactions at a site for full-round U insertion
Substrate discrimination in RNase P RNA-mediated cleavage: importance of the structural environment of the RNase P cleavage site
Substrate preference of a Geobacillus maltogenic amylase: A kinetic and thermodynamic analysis
Substrate-binding and catalytic roles of LYS194 in the C-terminus in human adenylate kinase by site-directed random mutagenesis
Substrate induction and glucose repression of maltose utilization by Streptomyces coelicolor A3(2) is controlled by malR, a member of the lacl-galR family of regulatory genes
Substrate orientation: A way towards higher quality monolayer graphene growth on 6H-SiC(0001)
Substrate-assisted nucleation of ultra-thin dielectric layers on graphene by atomic layer deposition
Substrate-induced array of quantum dots in a single-walled carbon nanotube
Substantial improvement of perovskite solar cells stability by pinhole-free hole transport layer with doping engineering
Substrate size and heterogeneity control anomalous transport in small streams
Substitution of isoleucine for threonine at position 190 of S-opsin causes S-cone-function abnormalities
Substrate binding and turnover by the highly specific I-PpoI endonuclease
Substitution of the degenerate smooth muscle (SM) alpha-actin CC(A/T-rich)(6)GG elements with c-fos serum response elements results in increased basal expression but relaxed SM cell specificity and reduced angiotensin II inducibility
Substrate tRNA Recognition Mechanism of a Multisite-specific tRNA Methyltransferase, Aquifex aeolicus Trm1, Based on the X-ray Crystal Structure
Substitution at carbon 2 of 19-nor-1 alpha,25-dihydroxyvitamin D-3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells
Substrate channels revealed in the trimeric Lactobacillus reuteri bacterial microcompartment shell protein PduB
Substituent Effects on the Cooperativity of Halogen Bonding
Substitution of alanine for aspartate at position 179 in the SHV-6 extended-spectrum beta-lactamase
Substrate-induced band gap in graphene on hexagonal boron nitride: Ab initio density functional calculations
Substitution of surface-exposed framework residues alters secretion of recombinant fusion protein Fv/Tumor Necrosis Factor in Escherichia coli
Substrate translocation and stimulated ATP hydrolysis of human ABC transporter MRP3 show positive cooperativity and are half-coupled
Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2
Substantially increased risk of cancer in patients with diabetes mellitus A systematic review and meta-analysis of epidemiologic evidence in Japan
Substrate specificity of serum DNA- and RNA-hydrolyzing antibodies of patients with polyarthritis and autoimmune thyroiditis
Substrate specificity of delta ribozyme cleavage
Substitutions for Cys-472 and His-509 at the active site of beta-galactosidase from Lactococcus lactis ssp lactis 7962 cause large decreases in enzyme activity
Substantial biases in ultra-short read data sets from high-throughput DNA sequencing
Substitutions of Ser for Asn-163 and Pro for Leu-264 are important for stabilization of lipase from Pseudomonas aeruginosa
Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing
Substrate specificity and identification of functional groups of homoserine kinase from Escherichia coli
Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin
Substantial effective sample sizes were required for external validation studies of predictive logistic regression models
Substituent Constants (sigma(-)(p)) of the Rotated Nitro Group. The Interplay Between the Substituent Effect of a Rotated -NO2 Group and H-Bonds Affecting pi-Electron Delocalization in 4-Nitrophenol and 4-Nitrophenolate Complexes: a B3LYP/6-311+G** Study
Substitution Effect in NICS Values in Tropylium Ion Derivatives: An Ab Initio Study
Substitution effects in phenyl and N-pyrrole derivatives along the periodic table
Substitution effects in N-pyrazole and N-imidazole derivatives along the periodic table
Substitution effects on neutral and protonated pyridine derivatives along the periodic table
Substrate/inhibition studies of bacteriophage T7 RNA polymerase with the 5 '-triphosphate derivative of a ring-expanded ('fat') nucleoside possessing potent antiviral and anticancer activities
Substitution of basic amino acids in the basic region stabilizes DNA binding by E12 homodimers
Substrate behavior of plasminogen activator inhibitor-1 is not associated with a lack of insertion of the reactive site loop
Substitution of just five nucleotides at and around the transcription start site of rat beta-actin promoter is sufficient to render the resulting transcript a subject for translational control
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
Substrate specificity of mutants of the hydroxynitrile lyase from Manihot esculenta
Substituent elimination from p-substituted phenols by cytochrome P450 - ipso-substitution by the oxygen atom of the active species
Substitution of conserved hydrophobic residues in motifs B and C of HIV-1 RT alters the geometry of its catalytic pocket
Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content
Substitutions in a flexible loop of horse liver alcohol dehydrogenase hinder the conformational change and unmask hydrogen transfer
Substantial regional variation in substitution rates in the human genome: Importance of GC content, gene density, and telomere-specific effects
Substrate specificity and sequence preference of G : T mismatch repair: Incision at G : T, O-6-methylguanine : T, and G : U mispairs in DNA by human cell extracts
Substrate Orientation and Specificity in Xanthine Oxidase: Crystal Structures of the Enzyme in Complex with Indole-3-acetaldehyde and Guanine
Substrate atomic-termination-induced anisotropic growth of ZnO nanowires/nanorods by the VLS process
Substrate recognition domains as revealed by active hybrids between the D-arabinitol and ribitol transporters from Klebsiella pneumoniae
Substrate binding and catalysis by ubiquitin C-terminal hydrolases: Identification of two active site residues
Subseasonal variations in salinity and barrier-layer thickness in the eastern equatorial Indian Ocean
Substrate Sequences Tell Similar Stories as Binding Cavities: Commentary
Substructure in lensing clusters and simulations
Substrate Specificity Overlap and Interaction between Adrenoleukodystrophy Protein (ALDP/ABCD1) and Adrenoleukodystrophy-related Protein (ALDRP/ABCD2)
Substrate specificity of and product formation by muconate cycloisomerases: an analysis of wild-type enzymes and engineered variants
Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine
Substrate-bound Crystal Structures Reveal Features Unique to Mycobacterium tuberculosis N-Acetyl-glucosamine 1-Phosphate Uridyltransferase and a Catalytic Mechanism for Acetyl Transfer
Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques
Substitution of fish meal by Jatropha curcas kernel meal: Effects on growth performance and body composition of white leg shrimp (Litopenaeus vannamei)
Substrate recognition by the cell surface palmitoyl transferase DHHC5
Substrate dependent talitrid amphipods from fragmented beaches on the north coast of Crete (Crustacea, Amphipoda, Talitridae), including a redefinition of the genus Orchestia and descriptions of Orchestia xylino sp nov and Cryptorchestia gen. nov.
Subset characterization of myeloid-derived suppressor cells arising during induction of BM chimerism in mice
Substrate Specificity of Human Carboxypeptidase A6
Substantia nigra hyperechogenicity in DYT6 dystonia: A pilot study
Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption
Substantiating the Influence of Pore Surface Functionalities on the Stability of Grubbs Catalyst in Mesoporous SBA-15 Silica
Substrate Specifity Profiling of the Aspergillus fumigatus Proteolytic Secretome Reveals Consensus Motifs with Predominance of Ile/Leu and Phe/Tyr
Substitutional Patterns in Boron Doped Heterofullerenes C60-nBn (n=1-12)
Subsurface Application of Manures Slurries for Conservation Tillage and Pasture Soils and Their Impact on the Nitrogen Balance
Subsets, expansion and activation of myeloid-derived suppressor cells
Substance use and risky sexual behaviours among sexually experienced Ghanaian youth
Substitution and proton doping effect on SrZrO3 behaviour: high-pressure Raman study
Substance P Stimulates the Recovery of Bone Marrow After the Irradiation
Subspecific origin and haplotype diversity in the laboratory mouse
Substituent effects in substrates on activation parameters in the bimolecular nucleophilic reactions in solution
Substituent effects in nucleophiles on activation parameters in the bimolecular nucleophilic reactions in solution
Substructure shake table test method using a controlled mass: formulation and numerical simulation
Substitutions at Position 105 in SHV Family beta-Lactamases Decrease Catalytic Efficiency and Cause Inhibitor Resistance