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The stability of duplexes involving AT and/or G(4Et)C base pairs is not dependent on their AT/G(4Et)C ratio content. Implication for DNA sequencing by hybridization
The synthesis of the Streptomyces reticuli cellulase (Avicelase) is regulated by both activation and repression mechanisms
The second-site mutation in the herpes simplex virus recombinants lacking the gamma(1)34.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2 alpha
The P200 protein of Mycoplasma pneumoniae shows common features with the cytadherence-associated proteins HMW1 and HMW3
The human gene CGT encoding the UDP-galactose ceramide calactosyl transferase (cerebroside synthase): Cloning, characterization, and assignment to human chromosome 4, band q26
The structural organization of the human skeletal muscle ryanodine receptor (RYR1) gene
The identification of a novel cDNA preferentially expressed in the olfactory-limbic system of the adult rat
The testis isoform of the phosphorylase kinase catalytic subunit (PhK-gamma T) plays a critical role in regulation of glycogen mobilization in developing lung
The role of Phe-92 in the Ca2+-induced conformational transition in the C-terminal domain of calmodulin
The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family
The genes for secretion and maturation of lactococcins are located on the chromosome of Lactococcus lactis IL1403
The lactose transporter in Leuconostoc lactis is a new member of the LacS subfamily of galactoside-pentose-hexuronide translocators
The gluEMP operon from Zymomonas mobilis encodes a high-affinity glutamate carrier with similarity to binding-protein-dependent transport systems
The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb(3)-type cytochrome oxidase
The MalT-dependent and malZ-encoded maltodextrin glucosidase of Escherichia coli can be converted into a dextrinyltransferase by a single mutation
The mec-8 gene of C-elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts
The Azospirillum brasilense rpoN gene is involved in nitrogen fixation, nitrate assimilation, ammonium uptake, and flagellar biosynthesis
The Y1 gene of maize codes for phytoene synthase
The role of new information technology meeting the global need and gap of education in pediatric surgery
The transition to competency-based pediatric training in the United Arab Emirates
The Contribution of the Medical Education Partnership Initiative to Africa's Renewal
The human degree of care. Professional loving care for people with a mild intellectual disability: an explorative study
The catalytic potential of high-kappa dielectrics for graphene formation
The Effects of Thermoelectric Film Thickness on Performance of In-Plane Thermoelectric Modules
The importance of genetics in the diagnosis of animal diseases - A review
The 'Tyranny of Choices' in the Ingestion-Controlling Network
The topology of drug-target interaction networks: implicit dependence on drug properties and target families
The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors
The physiology of taste and smell: how and why we sense flavors
The effect of zinc on human taste perception
The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor: Evidence from the solution structure of G16A-MNEI
The need to feed: Homeostatic and hedonic control of eating
The dance of the clams: twists and turns in the family C GPCR homodimer
The neural differentiation gene Mash-1 has a distinct pattern of expression from the taste reception-related genes gustducin and T1R2 in the taste buds
The structure of S. lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain
The LisH Motif of Muskelin Is Crucial for Oligomerization and Governs Intracellular Localization
The pentapeptide LQVVR plays a pivotal role in human cystatin C fibrillization
The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central A beta Pharmacodynamic Responses in Mice, Dogs, and Humans
The Characteristic Structure of Anti-HIV Actinohivin in Complex with Three HMTG D1 Chains of HIV-gp120
The Immunocytokine F8-IL2 Improves the Therapeutic Performance of Sunitinib in a Mouse Model of Renal Cell Carcinoma
The quasar mass-luminosity plane - II. High mass turn-off evolution and a synchronization puzzle
The role of MeCP2 in CNS development and function
The Latency-Associated Nuclear Antigen Interacts with MeCP2 and Nucleosomes through Separate Domains
The Robotic Mouse: Understanding the Role of AF4, a Cofactor of Transcriptional Elongation and Chromatin Remodelling, in Purkinje Cell Function
The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome
The Autistic Neuron: Troubled Translation?
The Igf2/H19 imprinting control region exhibits sequence-specific and cell-type-dependent DNA methylation-mediated repression
The biological functions of T helper 17 cell effector cytokines in inflammation
The trivial function of steep
The human sleep-wake cycle reconsidered from a thermoregulatory point of view
The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM
The ups and downs of p53: understanding protein dynamics in single cells
The DNA-damage response: new molecular insights and new approaches to cancer therapy
The Checkpoint Kinase ATM Protects Against Stress-Induced Elevation of Cyclin D1 and Potential Cell Death in Neurons
The radiosensitizer 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide induces DNA damage in EMT-6 mammary carcinoma cells
The internal transcribed spacer 2 exhibits a common secondary structure in green algae and flowering plants
The Continuing Failure of Bexarotene in Alzheimer's Disease Mice
The role of autophagy in unilateral ureteral obstruction rat model
The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy
The pleiotropic roles of autophagy regulators in melanogenesis
The 24-bp consensus sequence responsible for regulation of the BphS1T1 two-component system in a hybrid promoter
The gene involved in X-linked agammaglobulinaemia is member of the src family of protein-tyrosine kinases (Reprinted from Nature, vol 391, pg 226, 1993)
The Aeromonas dsbA mutation decreased their virulence by triggering type III secretion system but not flagella production
The multiple roles of autophagy in cancer
The acquisition of resistance to TNF alpha in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray
The thrombin receptor second cytoplasmic loop confers coupling to G(q)-like G proteins in chimeric receptors - Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors
The complete sequence, expression in Escherichia coli, purification and some properties of carbonic anhydrase from Neisseria gonorrhoeae
The human hepatocyte nuclear factor 3 fork head gene FKHL13: Genomic structure and pattern of expression
The bphDEF meta-cleavage pathway genes involved in biphenyl/polychlorinated biphenyl degradation are located on a linear plasmid and separated from the initial bphACB genes in Rhodococcus sp. strain RHA1
The evolution of intergenic spacers of the 5S rDNA genes in the Drosophila obscura group: Are these sequences suitable for phylogenetic analyses?
The mutational spectrum in Treacher Collins syndrome reveals a predominance of mutations that create a premature-termination codon
The primary structure of Trypanosoma (Nannomonas) congolense variant surface glycoproteins
The human MCP-2 gene (SCYA8): Cloning, sequence analysis, tissue expression, and assignment to the CC chemokine gene contig on chromosome 17q11.2
The evolution of an intron: Analysis of a long, deletion-prone intron in the human dystrophin gene
The regional distribution and cellular localization of mRNA encoding rat prostacyclin synthase
The Salmonella typhimurium mar locus: Molecular and genetic analyses and assessment of its role in virulence
The tissue-type plasminogen activator inhibitor ETIa from Erythrina variegata: Structural basis for the inhibitory activity by cloning, expression, and mutagenesis of the cDNA encoding ETIa
The mottled mouse as a model for human Menkes disease: Identification of mutations in the Atp7a gene
The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites
The global conformation of an active hammerhead RNA during the process of self-cleavage
The anticodon loop is a major identity determinant of Saccharomyces cerevisiae tRNA(Leu)